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A Full Signals Checklist to Help AI Agents Conquer the Crypto Market

3 min readSep 25, 2025
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Thesis.io equips users and agent-space creators with powerful analytics through search and natural-language prompts. Use this checklist to query, combine, and compare signals to uncover both correlations and potential causal relationships.

Note: Some signals aren’t native in Thesis.io yet. You can still query them via Thesis.io’s deep web search (auto) to fetch the underlying data.

How to use this list:

Level 1: Single signal

→ E.g.: “What is sentiment of BTC over the last 24 hours?

Level 2: Multi-signal reasoning

→ For example: “Is there a relationship between daily sentiment and whale positions over the past 7 days?

Examples of known relationships (from research & industry)

  • Stablecoin issuance/flows ↔ BTC price
  • Attention (Google Trends, etc.) ↔ on-chain activity/returns
  • Investor-network structure → future crash risk
  • Twitter/X sentiment → short-horizon returns
  • Influencer/KOL events → short-run price/volume spikes
  • Google Trends spikes ↔ price/volume changes (feedback common)
  • Funding rates ↔ near-term returns/liquidations risk
  • Futures ↔ spot price discovery (two-way flow)
  • Leverage shocks → liquidation cascades
  • Order-flow imbalance (OFI) → returns/crash risk
  • DEX transaction cost mix → slippage/impact dynamics
  • BTC ↔ altcoins lead–lag patterns
  • Crypto ↔ macro/other assets (time-varying spillovers)
  • Developer signals ↔ longer-horizon repricing (context-dependent)

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FULL CHECKLIST

On-chain network & flow

  • Active addresses (active, new)
  • Transactions per block / total tx count
  • Fees, gas price, block utilization
  • Hash rate, difficulty (PoW)
  • TVL (by protocol/chain)
  • DEX volume, swaps count, unique traders
  • Bridge flows (in/out, by chain)
  • Stablecoin mint/burn, net issuance, velocity, peg deviation, on-chain reserves
  • Exchange inflows/outflows (by asset & by cohort), netflows
  • Whale transfer count/size, whale exchange deposits/withdrawals
  • Whale accumulation/distribution (cohort-based)
  • Wealth concentration: top-N holder share, share distribution
  • Staking/validator metrics: staking ratio, unlock schedules, validator health/slashing
  • DeFi risk state: borrow rates, utilization, liquidation queues, collateral mix, oracle deviation
  • MEV extracted, priority fees

Off-chain & information

  • Social sentiment indices (X/Reddit)
  • KOL/influencer posts, engagement, reach
  • Buzzword/Hypeword frequency & burstiness
  • Google Trends (by keyword/ticker/region)
  • News volume, headline polarity, source diversity
  • Developer activity: commits, releases, contributors, issues closed
  • Policy/regulatory events, lawsuits, approvals/rejections
  • Exchange/platform incidents: outages, halts, security notices

Perps, futures & options

  • Funding rate (level, changes), funding skew
  • Open interest (absolute, delta), long/short ratio
  • Basis/term structure (perp vs spot, futures curve)
  • Liquidations (count/size, bursts)
  • Implied volatility, vol surface/skew (options)
  • Perp volume by venue/asset

Orderbook & microstructure (CeFi/DEX with LOB)

  • Bid/ask spread, inside spread dynamics
  • Depth at top-k levels, aggregated depth
  • Order flow imbalance (buyer vs seller initiation)
  • Market order volume, large trade prints
  • Cancellation rate, spoofing/ layering flags
  • Queue length/priority, fill ratio
  • Slippage, realized price impact

Network graph & relations

  • Who-transacts-with-whom edges (address/cluster graph)
  • Cluster centrality (betweenness, eigenvector), PageRank
  • Community detection labels & dynamics
  • Exchange ↔ smart-money flow edges
  • Cohort flows: miners/validators, funds/MMs, insiders/dev multisigs
  • Graph connectivity: clustering coefficient, assortativity, diameter

Technical & derived indicators

  • Returns (log/simple), momentum, trend strength
  • Realized volatility/variance, realized skew/kurtosis
  • RSI, OBV, MACD, KDJ, Stoch, ATR
  • EMAs/SMA crossovers (e.g., 50/200), Bollinger bandwidth
  • Market breadth (advancers/decliners), new highs/lows
  • Composite scores (risk-on/off, mindshare, quality)

Market structure, sectors & stablecoins

  • BTC dominance, ETH dominance
  • Sector baskets: L1, L2, DeFi, NFT, Meme, AI, RWA
  • Rotation pairs/spreads (e.g., ETH/BTC, SOL/ETH)
  • CEX vs DEX volume share, venue concentration
  • Stablecoin share by issuer, pool imbalances (Curve/etc.), redemption flows
  • Cross-market: DXY, UST 2Y/10Y yields, CPI, VIX, SPX/NDX, gold, oil, SOX/semis

Events (time-stamped)

  • Protocol upgrades/hard forks
  • Token unlocks/vestings
  • Airdrops, listings/delistings
  • Hacks/exploits/bridge incidents
  • Governance proposals & outcomes
  • Chain congestion/outage episodes

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Oraichain Labs
Oraichain Labs

Written by Oraichain Labs

Layer 1 of AI blockchain oracle and Trustworthy Proofs. Find us at: https://orai.io | https://blog.orai.io

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